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Stronger CYP3A4 inhibitors including ketoconazole or itraconazole might be anticipated to have bigger effects than noticed with saquinavir. A starting dose of 25 mg of VIAGRA must be regarded as in people using erythromycin or powerful CYP3A4 inhibitors (like saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRATION, Scientific PHARMAC